Access downloadable resources from the Improving Care for Patients with Prolonged Symptoms and Concerns about Lyme Disease: A Clinician Toolkit.
Section 1: Welcoming patients
Section 2: Evaluating diagnoses
Section 3: Compiling a team
Section 4: Developing a Care Plan
Journal articles
Journal articles
Overview
Lantos PM, Rumbaugh J, Bockenstedt LK, Falck-Ytter YT, Aguero-Rosenfeld ME, Auwaerter PG, Baldwin K, Bannuru RR, Belani KK, Bowie WR, Branda JA, Clifford DB, DiMario FJ, Halperin JJ, Krause PJ, Lavergne V, Liang MH, Meissner HC, Nigrovic LE, Nocton JJ, Osani MC, Pruitt AA, Rips J, Rosenfeld LE, Savoy ML, Sood SK, Steere AC, Strle F, Sundel R, Tsao K, Vaysbrot EE, Wormser GP, Zemel LS. Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR): 2020 Guidelines for the prevention, diagnosis and treatment of Lyme disease. Clin Infect Dis.2021; 72(1), e1–e48. https://doi.org/10.1093/cid/ciaa1215
Wormser GP, McKenna D, Karmen CL, Shaffer KD, Silverman JH, Nowakowski J, Scavarda C, Shapiro ED, Visintainer P. Prospective evaluation of the frequency and severity of symptoms in Lyme disease patients with erythema migrans compared with matched controls at baseline, 6 months, and 12 months. Clin Infect Dis. 2020 Dec 15;71(12):3118-3124. doi: 10.1093/cid/ciz1215
Marques A. Persistent symptoms after treatment of Lyme disease. Infect Dis Clin North Am. 2022 Sep;36(3):621-638. doi: 10.1016/j.idc.2022.04.004
Ursinus J, Vrijmoeth HD, Harms MG, Tulen AD, Knoop H, Gauw SA, Zomer TP, Wong A, Friesema IHM, Vermeeren YM, Joosten LAB, Hovius JW, Kullberg BJ, van den Wijngaard CC. Prevalence of persistent symptoms after treatment for Lyme borreliosis: A prospective observational cohort study. The Lancet Regional Health-Europe. 2021;6:100142. doi: 10.1016/j.lanepe.2021.100142
Aucott JN, Yang T, Yoon I, Powell D, Geller SA, Rebman AW. Risk of post-treatment Lyme disease in patients with ideally-treated early Lyme disease: A prospective cohort study. International Journal of Infectious Diseases. 2022;116:230–237. doi: 10.1016/j.ijid.2022.01.033
Choutka, J., Jansari, V., Hornig, M. et al. Unexplained post-acute infection syndromes. Nat Med 28, 911–923 (2022). https://doi.org/10.1038/s41591-022-01810-6
Section 1: Welcoming patients
Kroll C. Questioning biomedicine’s privileging of disease and measurability. AMA J Ethics. 2021;23(7):E537-541. doi:10.1001/amajethics.2021.537
Clarke AE, Shim JK, Mamo L, Fosket JR, Fishman JR. Biomedicalization: Technoscientific transformations of health, illness, and U.S. biomedicine. American Sociological Review 2003;68(2):161-194. doi.org/10.2307/1519765
Section 2: Evaluating diagnoses
Lantos PM, Rumbaugh J, Bockenstedt LK, Falck-Ytter YT, Aguero-Rosenfeld ME, Auwaerter PG, Baldwin K, Bannuru RR, Belani KK, Bowie WR, Branda JA, Clifford DB, DiMario FJ, Halperin JJ, Krause PJ, Lavergne V, Liang MH, Meissner HC, Nigrovic LE, Nocton JJ, Osani MC, Pruitt AA, Rips J, Rosenfeld LE, Savoy ML, Sood SK, Steere AC, Strle F, Sundel R, Tsao K, Vaysbrot EE, Wormser GP, Zemel LS. Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR): 2020 Guidelines for the prevention, diagnosis and treatment of Lyme disease. Clin Infect Dis.2021; 72(1), e1–e48. https://doi.org/10.1093/cid/ciaa1215
Fitzgerald BL, Graham B, Delorey M J, Pegalajar-Jurado A, Islam MN, Wormser GP, Aucott JN, Rebman AW, Soloski MJ, Belisle JT, & Molins CR. Metabolic response in patients with post-treatment Lyme disease symptoms/syndrome. Clinical Infectious Diseases, 2021;73(7), e2342-e2349. https://doi.org/10.1093/cid/ciaa1455
Kobayashi T, Higgins Y, Melia MT, Auwaerter PG. Mistaken identity: Many diagnoses are frequently misattributed to Lyme disease. Am J Medicine 2022;135(4):P504-511. DOI: https://doi.org/10.1016/j.amjmed.2021.10.040
Bekhbat M, Li Z, Mehta ND et al. Functional connectivity in reward circuitry and symptoms of anhedonia as therapeutic targets in depression with high inflammation: evidence from a dopamine challenge study. Mol Psychiatry . 2022;27, 4113–4121. https://doi.org/10.1038/s41380-022-01715-3
Herrera JE, Niehaus WN, Whiteson J, Azola A, Baratta JM, Fleming TK, Kim SY, Naqvi H, Sampsel S, Silver JK, Verduzco-Gutierrez M, Maley J, Herman E, Abramoff B. Multidisciplinary collaborative consensus guidance statement on the assessment and treatment of fatigue in postacute sequelae of SARS-CoV-2 infection (PASC) patients. PM&R 2021;13:1027-1043.
Section 3: Compiling a team
Miller AH, Maletic V, Raison CL. Inflammation and its discontents: The role of cytokines in the pathophysiology of major depression. Biological Psychiatry. 2009;65(9):P732-741. https://doi.org/10.1016/j.biopsych.2008.11.029
Access the CME module
Access the CME module
